Our Science

OUR SCIENCE

Congress Presentations

This section includes posters and presentations related to Arvinas’ PROTAC science, discovery compounds, and clinical-stage assets presented at scientific congresses in the past three years.


AD/PD 2026 | Copenhagen, Denmark

Mar 17 - 21, 2026

Poster
Safety, Pharmacokinetics, and Pharmacodynamics of Multiple Doses of ARV-102, a PROTAC LRRK2 Degrader, in Participants With Parkinson’s Disease

L van de Bult et al.

SFN 2025 | San Diego, CA

Nov 15 - 19, 2025

Poster
ARV-102, a PROTAC LRRK2 Degrader, Modulates Pathways Associated With Parkinson’s Disease and Progressive Supranuclear Palsy: Proteomic Analyses of CSF From Non-human Primates and Healthy Volunteers

A Hendricson et al.

WMS 2025 | Vienna, Austria

Oct 7 - 11, 2025

Poster
Oral ARV-027 Induces PolyQ-AR Degradation and Improves Muscle Strength and Endurance in a Murine Model of SBMA

J Gregory et al.

MDS 2025 | Honolulu, HI

Oct 5 - 9, 2025

Poster
First-in-Human Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Ascending Doses of ARV-102, a PROTAC LRRK2 Degrader, in Healthy Participants

L Smits et al.

MDS 2025 | Honolulu, HI

Oct 5 - 9, 2025

Poster
First Clinical Trials of ARV-102, a PROTAC LRRK2 Degrader: Characterization of Pathway Engagement in Healthy Volunteers and Patients With Parkinson’s Disease

L Smits et al.

IAPRD 2025 | New York City, NY

May 7 - 10, 2025

Poster
First-in-Human Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of ARV-102, a PROTAC LRRK2 Degrader, in Healthy Volunteers

L Smits et al.

AD/PD 2025 | Vienna, Austria

Apr 1 - 5, 2025

Presentation
First-In-Human Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of ARV-102, a PROTAC LRRK2 Degrader, in Healthy Volunteers

L Smits et al.

Biennial International LRRK2 Meeting 2024 | Crete, Greece

Jun 18 - 21, 2024

Presentation
Development of Potent, Orally Bioavailable PROTAC® LRRK2 Degrader Molecules as Potential Disease Modifying Therapeutics for Neurodegeneration

K Kelly

MDS 2023 | Copenhagen, Denmark

Aug 27 - 31, 2023

Poster
Development of Potent, Orally Bioavailable, and Highly Selective LRRK2 PROTAC® Degrader Molecules as Potential Disease Modifying Therapeutics for Parkinson’s Disease

K Kelly et al.